In recent years, significant resources have been directed to collect experimental evidence of physical proteins binding, in an effort to infer and catalogue protein complexes and their multifaceted functional roles (Fields and Song, 1989; Ho et al., 2002; Ito et al., 2000; Uetz et al., 2000).
Previous studies have identified a multifaceted functional role of Notch signal in diverse cellular processes such as cell differentiation, proliferation, apoptosis, adhesion, migration, epithelial-to-mesenchymal transition (EMT), angiogenesis and oncogenesis (Artavanis-Tsakonas et al, 1999; Bolos et al, 2007).
Although the biochemical aspects of MMP function have been elucidated, their specific functional roles in the multifaceted nature of the disorder are not well understood.
Considering the diversity of plant GSKs and the multifaceted functional capabilities already observed, it is essential to gain more insight on their role in plant development and to extend the studies to other plant families than Brassicaceae.
OPG is a multifaceted molecule playing various functional role involved in cancer sustenance and progression such as tumor cell survival [ 4, 5] resistance to TRAIL induced apoptosis [ 6], angiogenesis and regulation of cellular phenotype [ 7].
But the theme has a functional role as well.
Lycan (1996) appeals to functional role.
Sift through and analyze the details, data, and metrics that you need for your functional role.
Its functional role was assessed in vivo.
Biomaterials applied in these clinical trials play a multifaceted role by functioning as carrier, barrier or reactor.
Thus, it appears that HARP plays a multifaceted role in regulating the function of RPA.
