Sentence examples for multifaceted diseases from inspiring English sources

Furthermore, alteration of miRNA expression in quiescent IBD tissues is consistent with the notion that genetic variants that result in differential gene expression (eg. that of regulatory molecules such as miRNAs) as well as mutations in the open reading frame are expected to contribute to multifaceted diseases.

Stroke and depression are complex and multifaceted diseases but both disorders have common pathological substrates that could be targeted by therapeutic intervention.

In summary we assembled a global pathway model for AKI based on proteomic changes, and further support the concept that the approach of in-depth Systems Biology coupled with high-resolution proteomic analysis represents a valuable approach to elucidate complex pathways and systems, especially in multifaceted diseases such as AKI.

For example, cystic fibrosis (CF) is a multifaceted disease that is present in about 1 in every 2,000 live births of individuals of European ancestry.

A combination of holistic systems biology approaches and traditional reductionist experimentation will be required for a nuanced understanding of this multifaceted disease process.

While Aβ and tau represent the two key pathological mediators of disease, other aspects of this multifaceted disease (e.g. oxidative stress, calcium-mediated toxicity, and neuroinflammation) are being unraveled, with the hope to develop a more comprehensive approach in exploring disease mechanisms.

Cancer is a multifaceted disease that represents one of the leading causes of mortality in developed countries.

Acute myocarditis (AM) is a "multifaceted disease" characterized by a large variety of acute manifestations, potentially followed by unpredictable sequelae ranging from dilated cardiomyopathy to recurrent arrhythmias [1, 2].

And since addiction is a multifaceted disease, treatment and recovery are often more complicated than getting an individual to simply stop using opioids.

As we study additional families and expand the phenotype of this multifaceted disease, we predict that patients/families will be identified in which seizures are an associated manifestation.

Psoriatic arthritis is a multifaceted disease.