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MultIethNic Study of BrEast ARterial Calcium Gradation and CardioVAscular Disease (MINERVA) was designed to answer the question of whether a novel continuous breast arterial calcification (BAC) mass score improves cardiovascular risk stratification among asymptomatic postmenopausal women.
In this multiethnic study of over 68,000 men, overall a history of prostatitis and longer duration of prostatitis symptoms was associated with an increased risk of prostate cancer.
Despite this concern, the UKPDS outcome model has been applied in multiethnic study samples [ 28, 29].
The genetic heterogeneity in our multiethnic study population is a major concern.
One multiethnic study demonstrated that the risk in non-Hispanic whites and Hispanics differed with that in African Americans (10).
Heart Positive (Clinicaltrials.gov ID NCT00246376) was a large multiethnic study of healthy patients with HIV infection on stable HAART [ 13].
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Overall, we show that there are substantial power gains to be had by focusing on large multiethnic studies.
Despite the important role of HDAC3 in tumor recurrence and its predictive implications, this study should be viewed as hypothesis generating, to be followed by larger prospective and multiethnic studies to confirm our findings.
The validity of available indicators of socioeconomic position is not yet established in multiethnic studies.
Unfortunately, other multiethnic studies have not considered differential sex effects across ethnic groups (10, 19, 20).
Large multiethnic studies with complementary individual- and area-level measures of SES are needed to corroborate our findings.
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