Sentence examples for multiethnic panel of from inspiring English sources

For genetic characterization of IGF1, 154 SNPs were genotyped a multiethnic panel of 349 individuals with no history of cancer (18).

All of the missense mutations involve conserved residues in regions of the protein that have postulated roles in enzyme activity; none of the mutations were reported in a multiethnic panel of 528 cortrols[22] or are present in the SNP database.

We sequenced the coding exons of 17 genes (EP300, CCND1, NME1, NCOA1, NCOA2, NCOA3, SMARCA4, SMARCA2, CARM1, FOXA1, MPG, NCOR1, NCOR2, CALCOCO1, PRMT1, PPARBP and CREBBP) suggested to influence transcriptional activation by steroid hormone receptors in a multiethnic panel of women with advanced breast cancer (n = 95): African Americans, Latinos, Japanese, Native Hawaiians and European Americans.

After conducting a 10-cM full genome scan with approximately 400 multiallelic markers for 238 individuals from a multiethnic panel of 62 multiplex SLE families, Cantor et al. [ 47] confirmed the linkage to four previously reported sites (1q23, 2q33, 16q12 to 13 and 17q21 to 23) and revealed four novel sites (3p24, 10q23 to 24, 13q32 and 18q22 to 23).

In this study, we systematically screened the coding exons of steroid hormone receptor coactivator and corepressor genes in a multiethnic panel of women with breast cancer in an attempt to identify and catalogue potentially functional coding polymorphisms that may serve as genetic markers of breast cancer risk.

Each amplicon was sequenced in 94 of the 95 subjects in the multiethnic panel, on average.

Romero et al. (2009) failed to find a bias when comparing the full set of 783 STRs used in the HGDP-CEPH dataset with a set of 16 unbiased STRs discovered in a multiethnic panel; however, the small number of markers in the unbiased set limits the power of their analysis.

For genetic characterization of IGFBP1 and IGFBP3 (which are located contiguously in a 35kb region of chromosome 7), 56 SNPs were genotyped in the multiethnic panel (18).

The reference panel is a multiethnic panel (with four identified super-populations, that is, Europeans [ n = 379], Africans [ n = 246], Asian [ n = 286], and Admixed Americans [ n = 181]) and has been shown to perform imputation of genotypes with high accuracy in admixed samples.

Although the power gain for alleles of lower frequency in CEU was noticeable in both multiethnic panels, the best power was obtained for the "cosmopolitan" panel with representation from the major continental groups as well as the admixed populations (Figures 1 and 2).

To identify regions of strong linkage disequilibrium, 64 SNPs in the gene encoding IGF1 and 36 SNPs in the genes encoding IGFBP-1 and IGFBP-3 were genotyped in a panel of 349 cancer-free women from the Multiethnic Cohort [ 37, 38].