Sentence examples for multi-point linkage from inspiring English sources
Multi-point linkage analysis was performed.
The multi-point linkage results on chromosome 4p16.1 are shown in Figure 1 and Table 2.
Low et al (2004) [32] carried out a linkage scan among UK Caucasians (affected sib-pairs) and confirmed linkage of CD to the 19p13.2 region (peak multi-point linkage score of 1.59).
Markers were assigned to linkage groups based on linkage supported by two-point LOD scores ≥ 3.0, and later ordered within these groups using multi-point linkage analyses employing a heuristic approach.
To illustrate the added benefit of this combined approach Figure 3 depicts the un-weighted GWAS p-values along with the multi-point linkage signal (in red) in Panel A alongside the newly linkage-weighted p-values and new significance threshold in Panel B for factor 4B(POST ADP.
The porous embedding and multi-point covalent linkage between enzyme and hydrogels strengthened the secondary structure stability of enzyme and thus enhanced enzyme stability in the presence of organic solvent and at high temperature.
The multi-point approach, FEstim assumes linkage equilibrium and may provide inflated inbreeding coefficient estimates if this assumption is violated [ 13].
Multi-point sib-pair based linkage analysis was performed using a microsatellite marker set, and single-SNP association tests were performed using markers from the Illumina 1 M genotyping chip from deCODE Genetics , Inc
In particular, the development of effective methods for immobilizing large multi-subunit proteins with multiple covalent linkages (multi-point immobilization) has been effective in stabilizing proteins where subunit dissociation is the initial step in enzyme inactivation.
High-density single nucleotide polymorphism (SNP) data also provide challenges for conventional multi-point pedigree methods because of linkage disequilibrium (LD) between markers and because subtle non-Mendelian genotype errors or inaccuracies of physical position can confuse estimation of the inheritance vectors.
Starting from the existing order of a linkage group, each marker assigned to that linkage group by two-point analysis, but not present on the multi-point map, was tested in every possible location.
