Multi-faceted connections to other major players of mitochondrial biogenesis and physiology, like the protein import machineries, the oxidative phosphorylation system, carrier proteins and phospholipid biosynthesis enzymes, are currently emerging.
While the mechanisms causing ventricular catheter shunt obstruction and down-stream shunt valve obstruction are likely multi-faceted, inflammatory cells certainly play a major role in shunt obstruction in pediatric and adult patients.
"We want to be a major player in delivering multi-faceted messaging to users".
The multi-faceted nature of the concept of self poses a major challenge in the search for the neural correlates of self-related processing.
Decreases in mortality and morbidity seen in the major trials of statins may therefore reflect multi-faceted actions on the atherosclerotic process.
While price is a major tool in seeking to govern behaviour, the multi-faceted reasons behind obesity will not be dealt with by a blunt rise in cost.
He said: "Security in any major Games is a very complex operation - multi-faceted, lots of moving parts.
By multi-faceted approaches using the model system Arabidopsis, my lab has made major breakthroughs in revealing the sites and regulatory mechanisms of GA biosynthesis.
It was here that the big four - Martha Graham, Doris Humphrey, Hanya Holm and Charles Weidman - hammered out the multi-faceted form of American modern dance, benefiting from residencies that culminated in major premieres and basic principles now familiar to all.
Multi-faceted Spanish producer/DJ/musician Henry Saiz original "Haunted Girl Canyon" is a summery, uptempo house shuffler with shimmery, major-key synths.
In an era where the body has become a major cultural currency, and the failure to tend it a moral transgression, the rich, multi-faceted experience of ageing has been pathologised and reduced to shame about looking old.
