Our researchers have previously developed many unique radiotracers, many involving multi-step sequences; for example, the F-18 (t1/2: 110 min) labeled catecholamines.
This streamlines the synthesis and increases the efficiency considerably, because pre-functionalization (often achieved within multi-step sequences) of substrate(s) is no longer required.
The complete dimerization process involves a complex multi-step sequence of events and a more in-depth analysis of all reaction steps will be accounted for elsewhere.
Synthesis of these compounds was carried out via a multi-step sequence consisting of copper-catalyzed azide alkyne cycloaddition (CuAAC) as a key step in aqueous media.
These compounds were synthesized via a multi-step sequence consisting of copper-catalyzed azide-alkyne cycloaddition (CuAAC) as a key step in aqueous media.
Expeditious synthesis of these compounds was carried out via a multi-step sequence consisting of few steps such as Gewald reaction, Sandmeyer type iodination, Sonogashira type coupling followed by iodocyclization and then Pd-mediated various C C bond forming reactions.
Elegant synthesis of these compounds was performed via a multi-step sequence consisting of MCR, Sandmeyer type iodination, Sonogashira type coupling followed by iodocyclization and then Pd-mediated various C C bond forming reactions.
Oesophageal adenocarcinoma usually arises through a multi-step sequence from Barrett's metaplasia to dysplasia and carcinoma [14].
Esophageal adenocarcinoma development experiences a long procedure through a multi-step sequence of metaplasia-dysplasia-adenocarcinoma.
The classic sigmoidal dose response of steroid-regulated gene products belies the complexity of a system which relies on an intricate, multi-step sequence of events to initiate transcription from a target gene (McKenna et al., 2009).
For instance, the retention duration of a multi-step sequence (remove the mitten from the puppet's hand, shake the mitten, replace the mitten; see Fig. 5) can be increased by manipulating a number of factors.
