These results confirm previous findings of antisaccade deficits in schizophrenia subjects and support the use of the antisaccade task as a potential schizophrenia endophenotype in multi-site genetic studies.
ENIGMA has not yet attempted a multi-site genetic study of brain connectivity.
Nakashima, J., Chen, F., Jackson, L., Shadle, G. & Dixon, R. A. Multi-site genetic modification of monolignol biosynthesis in alfalfa (medicago sativa): effects on lignin composition in specific cell types.
In response to these issues, we compiled, collated, and georeferenced available information on marine turtle biogeography – including individual nesting sites, genetic stocks, and geographic distributions based on monitoring research – to develop multi-scale Regional Management Units (RMUs).
The results show that multi-product multi-site scheduling problems can be effectively handled as mTSPs, and the proposed problem-specific representation based genetic algorithm can be used in wide range of optimization problems.
The COGS is a multi-site NIMH-sponsored investigation of the genetic basis of 12 primary and multiple secondary quantitative endophenotypes in schizophrenia.
The Project among African-Americans to Explore Risks for Schizophrenia (PAARTNERS) is a multi-site, NIMH-funded study that seeks to identify genetic polymorphisms that confer susceptibility to schizophrenia among African-Americans by linkage mapping and targeted association analyses.
The subset of potential genetic variations, deletions, insertions, duplications, and complex multi-site variants, is collectively referred to as copy number variants (CNVs) [ 1].
Meaningful genetic research requires large sample sizes that are best ascertained using multi-site study designs.
GS prediction accuracies for multi-site were high and better than those of single-sites while multi-site predictability produced the lowest accuracies reflecting type-b genetic correlations and deemed unreliable.
