As a consequence of this, the design of scaffolds for tissue engineering involves multidisciplinary and multi-scale aspects, the latter being the subject of intensive investigation by the research community.
Currently there is no technology available which supports both the collaborative as well as the multi-scale aspect in an adequate manner.
Hydrolytic degradation of individual chains occurs at the molecular level and mixture constituents diffuse individually accordingly to Fick's 1st law at the bulk level – such analysis confers a multi-scale aspect to the resulting reaction diffusion system.
This paper addresses the consequent need for design and simulation tools for engineers to make effective use of such structures by, as a first step, analyzing the multi-scale stability aspects of the superelastic behavior of a particular hexagonal, thin-walled, SMA honeycomb under in-plane compression.
As is typical of complex historical structures, a realistic quantitative computational assessment of the bridge response should address multi-physics, multi-scale, time-dependent and three-dimensional aspects of the problem.
Clues to understand the mechanisms involved are given, showing the multi-scales and multi-physical aspects of the problem.
We did not approach aspects of multi-scale modeling that occur in multi-organ physiology, or spatial aspects.
This book has three sections that group together different aspects of multi-scale quantum simulations.
The chapters presented in this issue reinforce key aspects of planning: multi-scale, and multi-faceted, yet integrative in its intent, stressing the physical, yet inescapably social.
The first aspect is a multi-scale model for shield tunnels, which provides five different levels of detail (LoD) representing the different levels of abstraction required throughout the planning progress.
It is a multi-stakeholder, multi-variable, multi-scale problem.
