QSAR investigations were based on Hansch's extra thermodynamic multi-parameter approach and receptor surface analysis (RSA).
This study thus demonstrates the importance of incorporating a multi-parameter approach in developing improved packaging with optimised vent hole designs.
The sensitivity analysis, as proposed by Rabinowitz and Steinberg [Rabinowitz, N., Steinberg, D.M., 1991. Seismic hazard sensitivity analysis: a multi-parameter approach. Bull. Seismol. Soc.
This article demonstrates benefits associated with the application of a standardized methodology for performing economic assessment and by maintaining strong correlation between multi-parameter approach and adopted performance criteria in terms of productivity, efficiency and reliability.
By using a non-cancer and a cancer cell line originally from the same tissue (colon), coupled with testing lectins for cell binding and for their effects on these cell lines in culture, this study describes a simple multi-parameter approach that has revealed some interesting results that could be useful in drug development strategies.
These ROC scores suggest that the multi-parameter approach that was developed can help to identify relevant TFs in the TF interaction network of CRC.
A multi-parameter approach, encompassing haemodynamic, microcirculatory and haematological assessment, was used to determine the impact of TRPV4 blockade on endotoxaemia pathophysiology, as described previously (Sand et al., 2015).
Since the 1960s, attempts have been made to evaluate the trophic status of lakes by quantitatively applying single-variable trophic indices and multi-parameter approaches (Xu 2011).
With proper testing techniques and multi-parameter approaches, one can better correlate the properties of blended cements with the expected level of damage.
We describe our work on multi-parameter approaches to ligand-based de novo design and studies that demonstrate its ability to successfully generate lead hops or scaffold hops between known classes of ligands for some example receptors.
Comparatively, multi-parameter approaches are more robust than single-variable trophic indices, because of the multidimensional nature of the eutrophication phenomenon in water bodies (Carlson 1977; Cruzado 1987; Xu 2008).
