Sentence examples for mucosal integrity of from inspiring English sources

The HtrA protease of Helicobacter pylori, which efficiently colonizes at the gastric epithelial of host cells, disrupts the mucosal integrity of E-cadherin and spreads inflammatory diseases including gastric cancer by cleaving the cell-cell adhesion of the host.

In fact, animal studies with antibodies against CGRP showed extensive mucosal damage [72, 73], suggesting a role of CGRP in maintaining the mucosal integrity of the gastrointestinal tract.

Arginine (ARG) and nitric oxide maintain the mucosal integrity of the intestine in various intestinal disorders.

Chemotherapeutic agents may also interfere with the mucosal integrity of the intestinal tract, resulting in extensive intramural air.

Rspo1 has also been shown to ameliorate colitis in mice by improving the mucosal integrity of the gut [ 32].

EGF deficiency secondary to anti-EGFR agents interferes with the mucosal integrity of the intestinal tract resulting in diarrhea, constipation, nausea and vomiting, and PI.

Gut has been known as an amplifier of systemic inflammatory response syndrome in the setting of shock, gut hypoperfusion [ 82] and intestinal edema [ 81] through the mechanisms including increased intestinal permeability, disruption of mucosal integrity, liberation of proinflammatory mediators, translocation of intestinal microorganisms and resultant endotoxinemia.

NO mediates multiple physiological functions in the gastrointestinal tract, including mucosal blood flow, maintenance of mucosal integrity, and maintenance of vascular tone.

Altogether, these processes result in a loss of mucosal integrity and translocation of microbial products from the intestinal lumen to systemic circulation [ 22].

Furthermore, gastric acid has the ability to interrupt several growth factors like fibroblast growth factor and epidermal growth factor which in turn may prevent the maintenance of mucosal integrity and restoration of superficial injury [ 2].

Alterations in this novel EGC self-protecting mechanism could lead to a higher susceptibility towards apoptosis and thus contribute to disruption of the mucosal integrity and severity of inflammation in CD.