Although the classic severe EBOV disease presentation is characterized by hemorrhagic events (petechiae, ecchymosis, mucosal hemorrhages and visceral hemorrhagic effusions), studies defining the molecular mechanisms of endothelial impairment are elusive.
Additionally, the cardia of the stomach showed mucosal hemorrhage.
Common toxicities included hypocellularity of spleen, thymus and bone marrow, leucopenia and mucosal hemorrhage and ulceration in the gastrointestinal tract.
Other signs of primary hemostatic disorders are small and/or many scattered ecchymoses as well as mucosal hemorrhages.
There were no findings of conjunctival or mucosal hemorrhage, conjunctival injection, or splenomegaly distinguishable from baseline in any group.
Most of the dengue physical examination findings were indistinguishable from baseline, including all cases of conjunctival hemorrhage, conjunctival injection, generalized lymphadenopathy, hepatomegaly, mucosal hemorrhage, and splenomegaly.
The aim of the present study was to examine the protective effect of sesamol on stress-induced gastric mucosal hemorrhage and ulceration in rats.
Sesamol decreased stress-induced gastric mucosal hemorrhage and ulceration, but it affected neither oxidative stress nor mucus secretion in gastric mucosa.
Among cases with bleeding, this amounted to skin petechiae or minor bruising in the majority, with mucosal hemorrhage noted in only 73 cases.
CE and enteroscopic studies have shown that NSAID use induces erythema, mucosal hemorrhage, erosions and intestinal ulceration in the small bowel, confirming previous autopsy data [ 49, 50].
