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In order to overcome this limitation, results obtained in normal appearing colorectal mucosa were analyzed using two different cut-off levels.
Biopsies of the NST and surrounding mucosa were analyzed for five different tissue types.
Mongolian gerbils were infected with H. pylori and DNA methylation levels in the gastric mucosa were analyzed over time.
Differences in target gene expression between tumor and adjacent normal mucosa were analyzed by the Wilcoxon signed-rank test.
Regions of hyperemia, hemorrhages and necrosis, both in apical and basal mucosa, were analyzed by a pathologist in a blinded fashion.
Tumors of grade I to IV from the tongue, cheek, gingiva, lip and oral mucosa were analyzed and compared to normal tissue from similar anatomical locations.
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Sinonasal mucosa was analyzed from 38 CRS and 6 controls.
Interleukin-6 (IL-6) and prostaglandin E2 (PGE2) in plasma and the supernatant fluid of colonic mucosae were analyzed using commercially available I RIA kits (Beijing Sino-UK institute of Biological Technology, Beijing, China).
Epidermal growth factor (EGF) in plasma and transforming growth factor-α (TGF-α) in colonic mucosae were analyzed using commercially available I RIA kit (Beijing Sino-UK Institute of Biological Technology, Beijing, China).
The rectal data set was taken from a previous study [43] in which 29 rectal carcinoma and 20 normal mucosa samples were analyzed on a oligonucleotide microarray containing 22,231 features.
The remaining 10 buccal mucosa samples were analyzed further.
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