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The size of the removed lesion with a safety margin was 2.1 × 2.0 × 0.9 cm (Fig. 2a), and the buccal mucosa defect was reconstructed as a pedicled BFP flap (Fig. 1b d).
A buccal mucosa defect can be successfully covered with a pedicled BFP flap, which was first described by Egyedi in 1977 for the closure of oroantral and oronasal communications secondary to oncologic resections [10].
A gastric or duodenal ulcer was defined as a mucosa defect at least 0.5 cm in diameter with a perceptible depth.
Criteria for exclusion were: (1) an oral mucosa defect other than related to tumour surgery; (2) need for an obturator or resection prosthesis and; (3) treatment with antibiotics for an oral infection the last 2 weeks before the start of irradiation.
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Surgeons are frequently confronted with finding an acceptable source of autologous grafts for reconstruction of oral mucosa defects.
It is recommended that the vertical design be used for reconstruction of buccal mucosa defects, and the transverse design for mouth-floor and facial defects.
Thus, there is a need to overcome these shortcomings of limited supply and donor site morbidity in the current surgical management/reconstruction of oral mucosa defects.
The microvascular surgery of patients who have received irradiation to the neck is particularly challenging, because of lack of available vessels due to previous neck dissection, skin and mucosa defects, and obliteration of tissue plane.
Progress has been made over the years in the development of tissue-engineered substitutes that mimic human oral mucosa, either to be used as grafts for the replacement of mucosa defects, or for the in vitro oral mucosa models while tissue engineering of oral mucosa is still in its infancy.
AEN is a rare clinical condition, which may arise from the combination of several factors, such as the ischaemic damage in hypoperfusion states, direct injury to esophageal mucosa and defects in repair mechanisms and the healing process due to malnourishment and debilitating conditions [ 1].
This is particularly because it necessitates a flap which will reconstruct both the maxilla and mandible along with any associated soft tissue defect, mucosa or skin without adding to functional and cosmetic problems for patient and technical problems for the surgeon.
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