The human XIST promoter contains a much smaller CTCF binding site as compared to the mouse Xist promoter.
Leucine-rich pentatricopeptide repeat-containing protein (LRPPRC) binds mature or unprocessed mitochondrial mRNA in vivo (24, 25) and is often found associated with another much smaller RNA-binding protein, SLIRP (SRA stem loop interacting RNA-binding protein) (26).
"Figure 4 Regarding figure 4 : since spanions and tiRNAs are approxiamately in the same size (whereas spanions are much smaller the polII binding sites) it would be much comprehensible if the distance between these elements would be presented as the distance between the 5' edges of both element types.
Collectively, these ChIP-seq experiments demonstrate extensive Twist1 binding to genomic sequences and indicate that Twist1 bound predominantly in a tissue-specific manner, with much smaller numbers of shared binding regions detected among ECCs, limb buds, and PNST cells.
αM2-cap mutations have large effects on gating but much smaller effects on agonist binding, channel conductance, channel block and desensitization.
Structurally, this may be explained by much smaller positively charged phosphoinositide-binding interface on the F-BAR domain of Syp1 compared to the BAR domain of Rvs161/167 (Reider et al., 2009).
The azimuthal lever arm range of the weak binding bridges is much smaller than the range found for the strong binding bridges, and is rather symmetric with respect to the lever arm position of the crystal structures consistent with inherent flexibility.
In contrast to the dramatic chemical shift changes induced by cTnI147−163 or cTnI144−163, those associated with drug binding are much smaller.
A much smaller complex was formed upon binding to a shorter duplex (16 bp) under the same conditions (0.3 M NaCl, pH 6.5, 55 °C).
Upon aligning the apo-Tr and biotin Tr structures, we found that the conformational change in Tr upon biotin binding is much smaller than for SA (rmsd 0.21 Å for Tr, 0.36 Å for SA).
