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"With AmeriCares there is a much shorter loop between what you do and the positive impact it has on a life," he said.
Moreover, it is absent in the modeled hIL-3:receptor dodecamer complex because IL-3R alpha has a much shorter loop in this region than GMR alpha (Figure S5A).
Ala189 at the end of a core β−strand makes a structural divergence between the two enzymes in which the Drosophila enzyme (Pro265) embarks on a long insertion to Arg314 compared to a much shorter loop region to Glu204 in the Streptococcal enzyme.
However, several plant NIPs have been shown to transport glycerol [ 65] and some of them have much shorter loop C with less than 20 residues.
Fungi XIPs, on the other hand, has much shorter loop C among all XIPs and its length is comparable to that of plant PIPs with 20 residues.
Although, it is tempting to correlate the length of loop C with the glycerol transporting property, several plant NIPs are known to transport glycerol [ 65] and they have much shorter loop C and their length is only half of what is observed in dicot XIPs and GlpF.
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The second hypothesis is that the C-terminus of TOR contains a variable insertion (in vertebrates, including the conserved motif with the S2481 and S2484 phosphorylation sites) that may lie on a surface where a much shorter surface loop lies on the surface of PI3K near the active site.
However, in the B3 enzyme the β3 β4 loop is much shorter, due to shorter β3 and β4 strands, and further away from the active site.
These non-standard base pairs effectively divide the long 'classical' loops into much shorter ones.
Comparing to the corresponding region in the mouse and electric eel AChEs, loop 2 of AgAChE is much shorter because it contains a region of deletion (Figure 1).
In addition, the process control loop for hand-guided inspection is not much shorter than the destructive test.
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