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In the same vein, while intersections of computational approaches may achieve a higher level of specificity, they also generally achieve a much reduced sensitivity [32].
Using r2 results in a much reduced sensitivity to this problem [ 27, 28].
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Like chicken TRPV1, rabbit TRPV1 exhibits much reduced capsaicin sensitivity (Gavva et al., 2004).
Due to its markedly altered inactivation properties, the N588K hERG mutant also exhibits markedly reduced sensitivity to Class III antiarrhythmic IKr inhibitors (sotalol, E-4031), with much less of an attenuation of the effect of Class Ia drugs (quinidine, disopyramide) [10,15,16].
Reduced sensitivity is inevitable in such circumstances.
Robustness means reduced sensitivity to perturbation.
Both moAbs detected oat prolamins, albeit with substantially reduced sensitivity.
However, contamination rates were much higher for the MGIT media, 17-24%, compared to 7% for BACTEC, suggesting that contamination was a major cause of MGIT reduced sensitivity.
Indeed, we found that the sensitivity of the spike rate to increasing inhibition was much reduced compared to the sensitivity to increasing excitation.
This is consistent with MEG being most sensitive to superficial sources, and the sensitivity being much reduced for deep sources (Cohen and Cuffin 1983; de Jongh et al. 2005; Goldenholz et al. 2009; Hillebrand and Barnes 2002).
However, infinitesimally small PET detectors are not feasible as the volume sensitivity would be much reduced.
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