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However, that does not appear to be the case as PAT2-mediated l-[H]pipecolic acid uptake is much reduced (p < 0.001) compared to [H]glycine due to a reduction in Vmax from 934 ± 22 to 224 ± 19 pmol oocyte− 1 (40 min)− 1 (Fig. 5F).
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Thus, male and female WT mice displayed a peak urinary corticosterone concentration that was 8-fold greater than the nadir value (P <.001), whereas the corresponding mean fold change of male and female CS mice was much reduced (1.5-fold, males P = ns and females P <.05) (Supplemental Figure 1).
Furthermore, we performed hot kinase assay by incubating purified ERK kinase with recombinant FBW7 proteins in the presence of gamma-P-ATP and indeed the incorporation of P was much reduced in T205A-FBW7 protein compared with WT-FBW7 (Supplementary information, Figure S4D).
We can also observe that the performance with suboptimal p is close to that with optimal p, but with much reduced complexity.
Indeed, if I simply divide the estimates (11) by N A the scatter of the residuals is much reduced, but a systematic trend with p remains.
The first SNP (78443-0_3537) illusthetes the value in subtracting the uncertainty value; although there was little change in the values of p for heterozygous individuals, the variation in the values of p for homozygous individuals was much reduced.
However, this interaction was much reduced when conduct and emotional problems were controlled, F (3,34) = 3.41; p < 0.05.
In other words, we see a statistically significant higher number of cases of much reduced, albeit functional, replication initiation in L. kluyveri than in the other two species (Fisher Exact Test p-values of 1.2e-8 and 3.6e-9 respectively).
And air-conditioning complaints were much reduced.
Children can get much reduced rates.
"The next generation will operate on a much reduced scale.
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