Sentence examples for much poorer substrate from inspiring English sources
Because of this difference, NF90 does not interact with PRMT1, is a much poorer substrate than ILF3 for PRMT1-dependent methylation, and does not modulate PRMT1 enzyme activity.
In the meanwhile, compared to BsNudF, EcNudF has a much poorer substrate specificity towards IPP, making IPP can't be efficiently hydrolyzed.
C5-Alk is a much poorer substrate, with KM 78-fold higher and kcat 400-fold lower compared with those of FPP (Table S3); attenuated catalytic activity was previously noted with that analogue using yPFTase.
This mutant Sog is a much poorer substrate for Tld cleavage compared to wildtype Sog, and no enhancement of cleavage in the presence of added Collagen IV is observed, contrary to that observed with wildtype Sog.
In contrast, for the bacterial enzyme, 3-methyl, 3-halo and 3,5-dihalokynurenines are much poorer substrates, while 3-fluoro, 5-bromo, and 5-chlorokynurenine have kcat and kcat/Km values comparable to that of its physiological substrate, l-kynurenine.
Compounds with methyl and ethyl alterations on C-2 are good substrates only in the (S) configuration; R2-aminobutan-1-ol and R2-aminopropan-1-ol are much poorer substrates, as well as 2-amino-2-methylpropan-1-ol, which bears two methyl groups at C-2 (Table 3).
In this sense, the nanocrystalline Fe78B13Si9 substrates possess much poorer wettability by molten Sn compared with their amorphous counterparts.
The attenuated helicase activity by Y130A is in line with previous data, in which XPD is a much poorer helicase when acting on a 5′ partial duplex substrate compared with a forked substrate (Pugh et al, 2008a).
The lack of a suitable proton donor within the active site of EGS to catalyze the carbon-oxygen bond cleavage may account for the requirement of EGS for an esterified substrate: coniferyl alcohol carries a much poorer leaving group (free hydroxide ion) than its acetylated form (the resonance-stabilized acetate ion) (see Figure 6C).
That includes much poorer places like Honduras.
