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Second, pigs infused with metformin also received much more fluids and norepinephrine (to treat hypovolemia and systemic vasodilatation) and glucose (to correct hypoglycaemia) than controls.
Hemodynamic changes are shown in Additional file 1. Pigs infused with metformin became hypotensive (P < 0.001) and therefore received much more fluids (final water balance 1172 ± 834 vs. -139 ± 242 ml, P = 0.011) and norepinephrine (< 0.001) than controls.
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It was so much more fluid.
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But today's economy is much more fluid.
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