In contrast, salmon Elovl5 transcripts were predominantly expressed in liver and intestine, with much lower expression in brain, and even less in other tissues [ 25].
Since the identified gene candidates were also expressed in susceptible cells, albeit at much lower expression levels, we examined whether gene knockdown in these cells might enhance their prion propagation kinetics further.
Furthermore, IHC analyses of the GG14 and GG16 xenografts and corresponding patient material revealed that both tumors similarly express YKL40, the established mesenchymal marker, contrasting the much lower expression level of this marker in GG14 cells in culture (Supplementary Figure 7a and Figure 7e).
From stage I to III, α -tubulin II fluorescent intensity was similar among all gametocytes at the same stage of maturity, yet stage IV and stage V gametocytes that reacted with anti-Pfg377 revealed much lower expression levels of α-tubulin II than those gametocytes not expressing Pfg377 (Fig. 4C, D, E).
Other genes commonly expressed at high levels in invasive carcinomas and of much lower expression in DCIS and normal breast tissues include lumican (LUM/LDC) (56.7-fold; P = 0.0011), versican (CSPG2) (18.2-fold; P = 0.0017), vimentin (VIM) (17.7-fold; P = 0.0014), decorin (DCN/PG2) (13.9-fold; P = 0.0007) and adlican (DKFZp564I1922) (12-fold; P = 0.0086).
Muse cells also exhibit much lower expression of the so-called "Yamanaka factors" in comparison with iPS cells (>105 fold decrease) [25].
These transcripts comprised less than 1% of the responsive transcripts and had much lower expression levels than RAP-representative transcripts for all conditions.
The results showed that Hpa expression was much higher in HepG2, SGC-7901, MKN45, SW480, and U2OS cells, whereas much lower expression of Hpa was detected in MCF-7 cells (Fig. 1).
Whereas the PAMAM/DNA complexes directly supported on the star poly(dl-lactide) film showed a much lower expression level for HEK293, which indicated the existence of PHEA played an important role in the efficient transfection.
Comparison of 42 samples examined by both RNA-seq and microarray revealed marked differences in sensitivity, with transcripts identified only by RNA-seq having much lower expression than those also identified by microarray.
The former showed much lower expression levels than the later, though they contained comparable anthocyanins.
