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We would need to see data from much longer studies that look at the total health impact of selenium or vitamin E supplements before we could say if the small effects on the chance of getting prostate cancer suggested by this study outweigh any general benefits to health.
That is a promising sign, Townes says, but much longer studies would be needed before the technique could be considered safe enough to try in humans.
Our hope is that this paper will be a small but inspiring step toward the development of larger and much longer studies.
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Several said in interviews that they were open to the mayor's proposals, but thought that the ideas merited much longer study.
Other studies, particularly those that generated content from scratch reported much longer study periods [ 13, 26].
It is long enough to demonstrate the effect, but the ideal would be a much longer study.
In case of the first situation a (much) longer study period may be required than in the latter situation.
In the present post hoc analysis, moderate weight gain (0.8-3.8 0.8-3.8 observed during the much longer study period (median = 204 days, range = 6 to 1009 days).
Whereas in parallel group CRTs the inclusion period can be extended rather easily, this is not straightforward in SWDs since it would mean that the time between steps needs to be prolonged which may result in a much longer study period than planned beforehand.
A much longer study will be required to determine whether the frequency of discordant visual acuities does correlate with disease duration, as suggested by the literature (Newman et al., 1991; Riordan-Eva et al., 1995), but this would not alter our main conclusions.
Crawford said much longer term studies were needed to confirm the extent of any effect of omega-3 on children's brains at school age.
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