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However, this process strongly suffers from much longer induction periods, i.e., the catalyst requires about 300 h to reach CH conversion of ca. 35 % and needs 600 h to get higher amounts of adipic acid in the product stream, which makes the process commercially unattractive.
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Requiring a much longer OGD stimulation for AD induction should be largely due to the low Na+ and zero Ca2+ ions used in our bath solution, which diminished the influx of Na+ and Ca2+ through their respective voltage-gated channels and ionotropic glutamate receptors [17], [18], [32].
In models of kidney disease, usually young mice undergo 1 2 weeks of disease induction, whereas aging involves much longer period of disease progression with repair mechanisms very likely disabled.
Similarly, genes that responded only to severe deficiency in batch culture usually required much longer periods of zinc withdrawal (8 hours) for induction to be observed.
When the hydroxyl terminal groups of the HBP were transformed into benzoate groups, the induction time for cure reaction became much longer and the heat of cure was reduced.
Due to the consistent remission induction and prolonged remissions, the overall survival (OS) time was much longer for the CD19L sTRAIL + TBI group than for the other groups (Fig. 5D).
In cell culture EMT induction in response to drug treatment or to growth factor stimulation occurs over a much longer period ranging from a few days to several weeks 26, 30.
In HSCT, more intense chemotherapy is applied than in induction or consolidation chemotherapy, and total body irradiation is also given, so the duration of neutropenia is much longer and the defect in immunity is more profound.
But how much longer, how much longer?
Maybe not much longer.
Much longer, hopefully.
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