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In vitro studies have revealed that tumor cells carrying non-T790 M mutations show a partial resistance to EGFR-TKI, but are much less resistant compared to cells with T790 M.
The particularly high values obtained for the sCJD VV2 subtype are in agreement Saverioni et al who showed that VV2 has the highest PK-resistance among sCJD types and that VPSPr is much less resistant [ 20].
The remaining 10 men (including Shackleton, foolhardy but always gentlemanly) used woolen sleeping bags, much less resistant to the brutal cold.
These parties will be much less resistant to compromise than the faction leaders, who will feel more impassioned about their positions.
It turned out that the lab strain, which had never been exposed to insecticides, was so much less resistant to them than wild mosquitoes that it couldn't compete in the heavily sprayed release area.
In addition, we had also shown that an etk knock-out mutant is much less resistant to polymyxin than a wild-type E. coli K-12 strain.
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Compared with the near-stoichiometric SiC matrix layers, the O-contained boundaries between deposited matrix layers and the designed Si-rich SiC matrix layers were much less corrosion resistant and preferentially corroded.
Aspergillus niger phytase shares 66% sequence identity, however, it is much less heat-resistant.
It has a greater tensile strength than chrysotile asbestos but is much less heat-resistant, fusing to black glass at relatively low temperatures.
Annual damage to brick-wood building was smaller than composite masonry building due to its limited exposure, although it is much less wind-resistant than composite masonry building.
Binding of 35S in lung slices from resistant rats is much less than in controls, and resistance cannot be explained by differences in either whole body metabolism or redistribution of thiourea in vivo.
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