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It's much less functional as it does not try to say, "Do the better rules arise or do the poorer rules arise".
The patients who now feed clinical trials differ from those pre-1965: 1) much less depressed (not melancholic, not delusional, not suicidal, much less functional disability 2) diagnosis by checklist criteria, not by daily observation in a closed habitat with attention to clinical significance, and; 3) patients recruited by advertisements.
In contrast, addition of both Gal and GalNAc to the ldlD-LG cell culture media resulted in producing much less functional glycans in the cells despite all glycosylation pathways are supposed to be restored in this condition.
SMN2 is a nearly identical copy of SMN1, which expresses much less functional SMN protein.
We can only speculate why the COP1 gene appears to be subject to much less functional divergence than SPA1.
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"I saw soldiers with horrific injuries that conventional treatment could not even hardly close, much less make functional," he says.
Nobody wants any of the top jobs in the state, and if things are going the way they are, then we won't have any government in New York, much less a functional one.
First, our TRN is based on expression data and transcriptional changes do not fully account for changes at the protein level, much less for functional activity of post-transcriptionally regulated proteins [ 88, 89], which may result in phenotypic changes not recapitulated by the transcriptional response.
Our results indicate that, at fine spatial grain, macro-environmental drivers are much less important for functional trait composition than has been assumed from floristic analyses restricted to co-occurrence in large grid cells.
Thus observations in vitro, while revealing what dynamics the CNS is intrinsically capable of, may not even show the dynamics that are actually instantiated in it in behavior, much less what their functional significance is.
The unit manager and social workers have explored all options and the only place to discharge Jean-Marc is to a complex continuing care facility where patients are on average much older and less functional than Jean-Marc.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com