Of those, few have ever been reviewed by the F.D.A. for safety, much less for efficacy.
In the wake of such recent citizen-mediated news events as the Asian tsunami, Hurricane Katrina, the London tube bombings, senator George Allen's political suicide, the Virginia Tech massacre, et al, the real question is why anyone would still wonder about the possibility, much less the efficacy, of so-called citizen journalism.
Again using the two extremes as illustration, the benefit of adding HCW decolonization is much less sensitive to the efficacy of patient isolation when few HCWs are responsible for many acquisitions.
This is an unusual occurrence in oncology, with the much more common pattern being less efficacy seen outside of a pivotal clinical trial.
Much less research has documented the efficacy of interventions designed to manipulate those presumed causes and correlates.
Although a favorable finding in this outcome is most desirable, the measures used are much less precise than those for efficacy and adverse effects.
In Latin America, there is much less data on AmBisome's efficacy.
Whereas in the case of late vaccination (Late vac), as the same vaccine was given when the tumor size had already reached 200 mm, its efficacy was much less potent.
Amino-acid residues influencing C1q binding can also be manipulated to alter CDC activity, although the contribution of CDC to clinical efficacy is much less well described than that of ADCC.
Notably, with respect to functional selectivity, it is widely regarded that morphine and other lower-efficacy agonists induce much less rapid MOR desensitization at somatodendritic receptors compared with higher-efficacy agonists.
