While osteocytes throughout the skeleton are located frequently 0.1 mm or further from the circulation and hence their source of nutrients, osteocyte death is much less prevalent in more actively remodelling bone such as the iliac crest.
This cytokine is highly toxic for actively proliferating OPCs, much less so for immature oligodendrocytes, and not at all for mature oligodendrocytes [ 65].
Multiple lines of research efforts in a variety of disciplines have provided evidence that traditional lecture approaches to teaching are much less effective than teaching approaches that actively engage students in the learning process (Bransford et al., 1999; Handelsman et al., 2006; Freeman et al., 2014).
The potential for emotional conflict is apparent in the accounts of parents of babies receiving treatment on NICU [ 29], who were united in wanting to be considered the primary decision-maker for their baby, but were much less consistent in wishing to be actively involved in decisions which they viewed as serious.
The energy-generating functions associated with these genes are most necessary when the seeds are young, green, and actively photosynthesizing and growing, and much less needed when the tissue has begun to yellow and desiccate.
Many other multigene families probably undergo processes similar to those we study here, but would be much less apparent than in the very diverse and actively evolving family of MHC class I molecules.
Confluent, quiescent endothelial cells were much less sensitive to the cytotoxic effect of aplidine than actively proliferating cells (IC50 was more than 10 times higher), even at long exposure times (72 h, not shown).
Assume that nobody around you wants to be actively aware that you are using your device, much less what you are doing with it, and be discreet.
Given the age of the interviewed patients, the trend towards controlling existing diseases, informing oneself actively about disorders, and being critical about medication is rather surprising: Interviewees had much less paternalistic expectations toward their GP than one would expect.
This difference may be of particular interest since perinuclear region contains actively transcribed genes whose expression might be controlled by 5metC in normal B cells but much less in CLL cells.
