(response items: completely recovered, much improved, improved, same, worse, much worse).
Response Scale: Much improved; Improved; Somewhat improved; No change; Somewhat worse; Worse; Much worse/much less control Q2.
Global perceived effect will be measured with a 6-point Likert scale with categories: completely recovered, much improved, improved, no change, worse and much worse.
Global perceived effect will be dichotomised to either success (completely recovered, much improved, improved) or no success (no change, worse, much worse) and expressed as relative risk reduction and numbers needed to treat.
For physical function, patient responses were anchored by the question; 'Compared to your FIRST EVALUATION at the University Orthopaedic Center: how would you describe your physical function now?'(much worse, worse, slightly worse, no change, slightly improved, improved, much improved).
This single-item measure asks participants to describe their change in pain on a 7-point rating scale with the following options: "very much improved," "much improved," "minimally improved," "no change," "minimally worse," "much worse," and "very much worse".
Ratings on a 7-point scale are dichotomized as improved (completely recovered and much improved) and not-improved (slightly improved, not changed and slightly/much/vastly worsened).
The distributions of the assessments (very much improved, much improved, minimal improvement or same/worse), were similar between physicians and patients, and in agreement 70.3% of the time; physician-patient agreement was higher in Turkey than in Sweden (73% vs. 61%, p = 0.040).
Clinical Global Impression scale (CGI) will be used to assess the response rate by rating the proportion of responders with a CGI improvement rating of "very much improved" or "much improved".
The categories of improvement included the following: completely recovered, much improved, slightly improved, not changed, slightly worse, much worse, and vastly worsened.
In previous trials of adults with ADHD, clinical response has been defined either as at least a 30% decline from baseline in symptom scores on a validated rating scale of adult ADHD symptom severity [ 6, 23, 24] or as very much improved or much improved on ratings of global improvement at endpoint [ 3, 4, 25].
