Paradoxically, molecular traits, such as gene expression, methylation, protein or metabolite levels, typically have a lower heritability, but sometimes individual genetic variants show much higher effect sizes on these traits.
In our study the results for the association between SHS exposure and IHD indicated much higher effect sizes for women.
In the second case, we performed coalescent simulation running backward in time, which allows simulations of much higher population sizes.
31 Sheard and McGuire also noted that the higher quality trials tended to produce much higher effect sizes than those of lower quality (0.63 vs 0.24).
45 Secondly, where placebo effects are less apparent, in, for example, the prevention of depressive relapse, antidepressants show much higher effect sizes, usually greater than 0.5.
Remission end points require much higher sample sizes of ∼200 patients per group (equals N=800 for this study), and these are targeted for pivotal studies.
Moreover, the laser diffraction data (obtained before significant evaporation could occur) appears to support this theory, showing much higher particle sizes than those obtained from cascade impaction studies [ 26, 30, 31].
[ 18] Both of these studies reported much higher effect sizes than demonstrated in our study and demonstrated expected known group differences, namely that caring for a child with a chronic condition and medical needs at home results in worse parent HRQL and worse family functioning.
Based on this hypothesis and the fact that the much higher pool size of ADP and AMP on Glc/Glu, we inferred that the the ratio of ATP/AMP was lower on Glc/Glu than on Glc.
As In is the main element in ITO, with a high E a (15.15 kcal mol−1) and low ΔE (1.68 kcal mol−1), it plays the main role in the adsorption and growth of nanoparticles on graphene, because much lower ΔE for In on graphene tends to produce a much lower density of nanoparticles with a much higher particle size [40].
