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Hyper-osmotic stress induces phosphorylation at both sites but there is a much higher induction ratio at S747.
Similarly OAS1a showed much higher induction in ME7 + poly I C animals than in NBH + poly I C animals.
Only, Ruiz de Almodovar et al (1994) found a much higher induction frequency of about 66 dsb × 10−12/Gy/Da.
We also observed a much higher induction of hepatic CYP2E1 after acute alcohol treatment in Fxr KO than that of WT mice, which may contribute to exacerbated alcohol-induced liver injury in Fxr KO mice.
Moreover, the concentration of some phytoalexins, such as scoparone, increases in the flavedo in response to P. digitatum attack, although a much higher induction is achieved by treatments that increase resistance in the fruit [ 4, 5].
Basal ER-transcriptional activity was not affected in these cells (as assessed by the level of progesterone receptor), but estrogen stimulation led to a much higher induction of ER activity than in parental cells.
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While the diurnal patterns reported in this study have been previously identified, other studies have reported much higher inductions ratios for Fe-deficiency-inducible genes including OsNAS1 and OsNAS2 (Inoue et al. 2003; Kobayashi et al. 2009).
Although higher concentration of doxorubicin alone induced apoptosis, nanoparticles loaded with doxorubicin exhibited a much higher apoptosis induction rate in both drug sensitive and resistant cell lines.
Furthermore, we used FACS analysis and showed that MLN4924 induced remarkably more apoptosis in Atg5−/− MEFs than that in Atg5+/+ cells, as reflected by a much higher fold induction of sub-G1 population in Atg5−/− MEFs.
QCIMFI is activated at lower concentrations of LG335 and has much higher fold inductions than RXRwt.
Of note in HUVECs, the induction of P16 expression was much higher than P21 induction: comparing fold changes).
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