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The scientific "skeptic," Michael Shermer (2008), plausibly suggests that the tendency to make sense out of non-sense evolved in human beings because missing a real pattern potentially has much higher evolutionary costs than noticing a false one; e.g., to mistake the wind in the grass for a lion is much more dangerous than the reverse.
As observed previously, protein residues that are predicted to be disordered generally evolve more quickly (i.e., have much higher evolutionary rates) than those in structured regions.
We detected very low sequence diversity of the human Cpn isolates and a much higher evolutionary distance of the animal isolates confirming results from previous studies [ 12, 19].
In addition, strong functional conservation may lead to above-expected sequence conservation even at much higher evolutionary distances that separate the two pairs.
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Evolutionary divergence between the two clades is between 0.033 and 0.038, much higher than the evolutionary divergence among H. ovalis populations.
Within the transmembrane domains (S1 to S6) and pore region the sequence similarity is much higher (>90%), suggesting evolutionary conservation of these regions responsible for channel function.
These findings suggest that the evolutionary pressure was much higher in maintaining the palindromic structure rather than the sequence conservation.
In contrast, CYB3 and CYB1 partitions are much less informative than GHR3 despite higher evolutionary rates that would have allowed the accumulation of a larger number of synapomorphies.
Blount et al.[ 3] determined that the probability of this evolutionary event is much higher when experimental evolution is replayed from samples frozen shortly before its initial appearance.
If the effect of every possible mutation, and interactions among mutations, on an organism's fitness was known, we would have a much higher probability of successfully predicting the evolutionary trajectory in response to a given selection pressure such as drug treatment or insecticide use.
This is much higher than the previous reports [ 7, 8] indicating the higher evolutionary rate of HIV-1C in Ethiopia and that HIV-1 variants containing these mutations are circulating in the absence of etravirine in the country.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com