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From Table 1, it can be found that much higher dosage of Na2O (10.5 %) was provided in pond ash-artificial aggregate mixture than pond ash.
So on April 19 , 1943 with a trip-sitting lab attendant at his side, Hofmann dropped a much higher dosage of LSD.
However, to eliminate the growth of the normal yeast strain on plates requires much higher dosage.
Firstly, a much higher dosage of TA (more than 4 mg) was given in previous study [ 16].
On the other hand, small animals needed a much higher dosage than humans, as was demonstrated by Mordenti and Chappell (1989).
However, inhibition of other protein kinase receptor autophosphorylation was demonstrated in FLT3, CFMC, c-FMC, v-fms and v-SRC, although at a much higher dosage (IC50>10 μ M) (Capdeville et al, 2002; Kurzrock et al, 2003).
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Florida also uses the drug, at much higher dosages.
Furthermore, much higher dosages of ATO are required for treating malignancies rising from solid cancers [12] in comparison to haematopoietic ones due to their distinct differences in tissue architecture.
The authors caution, however, that these tests were conducted at much higher dosages than would be encountered normally (Wiesner et al. 2006).
In human studies on cancer treatment, in contrast, DSG was applied intravenously at much higher dosages and was still generally well tolerated [ 37, 38].
9 These positive findings for alpha-tocopherol in the ATBC trial stand in contrast to those recently reported by the Physicians Health Study III (PHS II) trial which evaluated much higher dosages of alpha-tocopherol for shorter periods.
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