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Protection by RABV NAbs was further confirmed by using the WHO standard (Figs 5a, c) in which values > 0.5 IU/ml are considered protective against RABV; every group achieved IU/ml values much higher than 0.5 IU/ml, indicating that the addition of LASV GPC in the RABV backbone did not compromise its ability to generate RABV NAbs.
Moreover, MIDGE-vectors are devoid of plasmid backbone DNA and therefore have a smaller molecule size, so their effective transgene dose per microgram DNA is much higher than that of conventional plasmids [ 30].
(Much higher).
Production was much higher.
How much higher?
They were much higher.
But it could be higher — much higher.
The risk level is much, much higher.
Stimulus jobs much higher still.
(Other estimates are much higher).
"The stakes are much higher".
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