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They found that p-endosymbionts acquired by insects less than 100 million years ago (mya) have a much greater mutation rate in this gene than in associations greater than 100 mya.
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Other measurements of the extent of LGT within a species suggests that recombination plays a much greater role than mutation in generating diversity in MLST loci for B. pseudomallei.
In some cases, gene mutations in the 'downstream' proteins may have a much greater impact than mutations in genes expressed early in the inflammatory response.
Although mutations of 3 m1 and 2 m3 together had a much greater effect than 3 mutationion alone, the 3 mutationion alone had a considerable effect on the trafficking behavior and activity of long PINs.
From the metabolite profile at the V stage, it would appear that the impact of the gln1.3 mutation was much greater than that of the gln1.4 mutation.
If this product is much greater than one, then mutations of interest (e.g., driver mutations, resistance mutations) are ubiquitous; if the product is much less than one, then they are rare.
The several hundreds to tens of thousands of somatic mutations in each cancer, therefore, potentially allow much greater resolution of mutational patterns and insights into underlying mutational processes.
Additionally, several authors have pointed that intraspecific mutation rates are much greater than substitution rates between species as mutation rates decrease over time [ 25, 26].
However, the success of finding at least some functional coding sequence mutations underlying QTL coupled with the much greater reliability with which such mutations can be identified at the present time suggests that searching for functional coding mutations is a worthwhile initial approach for QTL analysis.
If these asexual species were truly ancient, then one would expect the minimum sequence divergence to be much greater, reflecting the many mutations since they last shared a common ancestor.
A much greater effect of gi mutations on SOC1 expression in the shoot apex would be expected as there is strong up regulation of SOC1 in the shoot apex in LD [ 23, 24], but this would be greatly diluted in our experiments as we examined SOC1 expression in total aerial parts of young plants.
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