"much further upstream" is correct and can be used in written English.
You can use it to refer to a point in a stream or river that is at a greater distance from the location of someone or something than it was before. For example, "The fish moved much further upstream after heavy storm rains raised the river level."
And my vision of participatory science is much, much further upstream before the table is set, before the the the money is invested.
"There is lab data showing this approach could be effective in malaria as well, but that is much further upstream," said O'Neill.
A third must-do is to take a long-term view: the really big prize lies much further upstream, where compelling evidence is emerging of return on investment from public health programmes and work in schools, communities and housing.
"We are very much further upstream in the preventative stage," she says.
More unexpected is the presence of motifs with positional bias much further upstream, in several tissue-restricted datasets.
Finally, subsequent studies have identified additional regulatory elements for Pmp22 that reside much further upstream of the gene (>100 kb), which could play a role in Pmp22 regulation.
But the battle for the Fallujah Dam may be a sideshow compared to that for much bigger Haditha Dam, further upstream on the Euphrates.
It happens much farther upstream, which is why incoming calls don't eat into your monthly minutes.
In contrast to the CREs in the core promoter, our knowledge of the positional and spatial arrangement constraints affecting regulatory elements further upstream is much more limited.
The 87th initially attempted to cross at Koblenz but met too much resistance there, compelling them to move further upstream closer to Boppard, where their crossing went smoothly.
The GA response element is located −194 bp upstream from ATG in the OPTX promoter (Additional file 1) and is found much further from the start of the gene in CHX21 (−1023 bp upstream from ATG; Additional file 1).
