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As illustrated in Figures 1B and 1C, a majority of the NPCs expressed Sox2, Nestin and Olig2, while much fewer cells expressed neuronal marker TuJ1.
In comparison, tissue sections from non-moribund mice had much fewer cells expressing OX40 (Fig. 5B) suggesting that expression of OX40 in the brain during Pb-A infection may correlate with disease progression.
Indeed, we observed much fewer cells with cycE overexpression in tumors treated with cycE siRNA as compared to those treated with PBS or control siRNA (Luc siRNA) (Figure 4D, cycE siRNA panel).
For somatic cells expressing PCNA, a similar pattern, but much fewer cells, were observed in ovaries of different developmental stages examined when compared to PCNA-positive oocytes (Fig. 2B).
However, because much fewer cells expressed CD44 in TgH than in WT mice, the CD4+ T cells in TgH mice appeared to be in an activation status different from that in WT mice.
As shown in Figure 6B, the stable 14-3-3σ-over-expressing 14-3-3σ-over-expressing 14-3-3σ-over-expressing 14-3-3σ-over-expressing 14-3-3σ-over-expressingtrol cells following γ-irradiation.
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The precursor pool does not expand as much, fewer cell columns are generated, and the resulting cortical surface area is reduced relative to the right-frontal and left-occipital regions (Fig. 4).
Wound-healing results demonstrated that much fewer Du145/Cyr61i cells moved into the wound area than the Du145/Ctrli cells in the same interval.
Interestingly, no enhanced male germ cell apoptosis was observed although the miR-dKO seminiferous tubules did contain much fewer germ cells compared to WT controls, suggesting that either the overall efficiency of spermatogenesis in miR-dKO testes is compromised, or the spermatogenic cells are depleted through a non-apoptotic manner.
At both 34 and 48 hpf, I found much fewer mitotic cells in the shh−/− mutant than in the wild-type retina (Fig. 7B, C).
In the sham group, a similar staining pattern was observed, with much fewer positive cells in the alveolar units (p < 0.05).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com