They took initiatives much earlier than the state institutions.
Secondly, we investigate the nonideal case that the worst estimation errors occur in the middle of state transition (MPDE); namely, the estimated transition moment is much earlier than the actual state transition.
That is, because submovements are not updated during execution (although a new submovement may commence before the previous one has completed), it is possible to identify the participant's intended movement at the onset of the submovement, which allows much earlier access to the state of the decision making process.
However, under the slow diffusion regime that prevails in vivo, OPI becomes significant much earlier, and the steady state is achieved when there are about 200 copies of the transposon.
But state insurance regulators say they need to start reviewing the new products — for compliance with federal and state laws — much earlier, in the first few months of 2013.
Stimson's oft-quoted observation that "gentlemen do not read each other's mail" appears in a passage of his memoirs in which he is explaining his much earlier decision, as secretary of state in 1929, to shut down the State Department-supported "Black Chamber".
2- TS and 4- TS are much earlier than the bimolecular transition state reported by Sousa and Silva that had C O and C Br bond lengths of 2.09 and 2.42 Å, respectively.
Within the broad reprogramming schedule, the roles of the individual four factors in reprogramming have been assessed [ 62] and it was found that c-Myc, in line with its possible role as a master regulator of the pluripotent state, acts much earlier than the other three factors during the reprogramming process.
McLaren later stated that, much earlier in the band's career, Vivienne Westwood had told him he should "get the guy called John who came to the store a couple of times" to be the singer.
