Sentence examples for much earlier activation from inspiring English sources

As a consequence of a weaker potential of ELF3Sha to repress PIF4 expression, a temperature increase could result in a much earlier activation of PIF4-mediated signaling processes during the night.

Studies reported here showed that ABL-N induced activation of JNK beginning one hour after ABL-N treatment and produced a sustained elevation for at least 24 hours in MDA-MB-231 cells, which is much earlier than the activation of caspase and the apoptosis.

On the other hand, failure of cell-cycle exit could activate p53, even though p53 activation occurs much earlier than cell-cycle exit in the shh−/− mutant retina (Figs. 5, S2).

Upon examination of genome-wide transcription and regulatory elements, we conclude that the B cell commitment to different activation states occurs much earlier than previously thought and involves a multi-faceted receptor-specific transcriptional landscape.

We suggest that perhaps Creb1 is activated in these cells much earlier for a specific interval to promote cell differentiation, and then activation is repressed in the same way as pCreb1 is eventually lost in distal epithelium by E18.5.

These only show UPR activation in aged mice, despite extensive pathology much earlier in younger mice [ 50].

We conclude that the B cell commitment to different activation states is dependent upon rapid regulatory mechanisms and occurs much earlier than previously thought.

These results indicated that the activation of EGFR and ERK driven by ECM1 was initiated by the events much earlier in the signaling cascade.

This observation suggests time-dependent activation of different mitochondriogenic programs, with induction of OXPHOS- and FAO-related genes occurring much earlier than stimulation of mitochondrial proliferation and increase in mtDNA content.

It should have happened much earlier.

Its woes, however, began much earlier.