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The more open active site architecture of RgDAAO is the origin of its much broader substrate specificity.
ATB0+ (SLCA14) is a transporter for numerous dipolar and cationic amino acids and thus has a much broader substrate specificity than the glycine transporters alongside which it is grouped on the basis of structural similarity 156.
We and others [11,12] introduced the control of seeking to mature the same cytochrome variants in the E. coli periplasm using the Ccm system, or System I, which has much broader substrate specificity than System III; it is able to carry out heme attachment under most circumstances when a CXXCH motif is present [24] irrespective of neighbouring residues.
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A recent study (Smith et al. 2015) suggests that TamB has a much broader set of substrates.
First, we wanted to obtain information about the effects of these variants on the uptake of a much broader spectrum of substrates than previously tested.
Given that Nbr affects the length of not only miRNAs, but also piRNAs, Nbr could potentially trim the 3′ends of a much broader species of RNA substrates, including other long and short noncoding RNAs and mRNAs.
Like other wild-type isolates [ 132], W encodes a large number of carbon source utilization genes, and it grows on a much broader range of carbon substrates than K-12 strains (Additional File 9).
When we compare C domain sequence motifs, it is apparent that motifs C2 and C4, despite being well conserved in LCL, are unconserved in Starter domains, which presumably can be explained by the much broader structural range of substrates processed by Starter domains.
It's much broader".
It is much broader and much deeper.
But the real problem is much broader.
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