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Dentine sialophosphoprotein (DSPP) was initially thought to be unique for dentine formation during tooth development, whilst recent reports have shown a much broader expression pattern such as in bone, periodontium and inner ear.
The CAG expansion in the protein huntingtin that causes HD is selectively detrimental to striatal medium spiny neurons and cortical pyramidal neurons, despite a much broader expression [5], [6].
Hence, our results indicate that human MAMDC1 has a much broader expression than its MDGA2 rat ortholog [28], as it is found at a low level in a wide range of tissues outside the nervous system.
Such clear spatial-temporal regulation was not observed for MtCCD7 nor MtCCD8 as both genes have a much broader expression pattern under non-symbiotic conditions.
Only recently it has become evident that meprins exhibit a much broader expression pattern, implicating functions in angiogenesis, cancer, inflammation, fibrosis and neurodegenerative diseases.
In contrast to the highly differential expression of ITIH genes, AMBP and TNFAIP6 exhibited a much broader expression pattern with differential gene expression restricted to kidney tissue.
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Rather, we are investigating materiality within the surrounding context, which encompasses a much broader domain than the expression form of language.
In all control embryos, GATA6 and GATA4 colocalise in PrE cells (3/3 embryos); however, we found that in 3/11 embryos treated with Gö6983, the domain of GATA6 expression was much broader than that of GATA4 (Fig. 6G).
Although this could influence the molecular evolution of bam, and potentially bgcn which is also transiently expressed (Ohlstein et al. 2000), it is unlikely to explain all selection acting on GSC gene evolution since piwi, Yb, stwl, and nanos have much broader patterns and timings of expression (Clark and McKearin 1996; Forbes and Lehmann 1998; Cox et al. 2000; Szakmary et al. 2009).
The dynamic range of expression obtained by messenger RNA sequencing can be much broader than that obtained by gene expression microarrays, allowing the detection of rare transcripts and more precise quantitation of expressed transcripts.
Shiny Varghese, deputy editor of the Indian magazine Design Today, said the Ambanis' house was the ultimate expression of a much broader trend.
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