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Most patients reported a much better efficacy of the triptans on residual migraine attacks compared to the pre-treatment period.
The Phase 2A trial showed much better efficacy, so there are a lot of questions surrounding this result".
In the treatment of lipopolysaccharide-induced uveitis, compared with 20 mg subtenon injection, suprachoroidal 2 mg TA demonstrated much better efficacy with significantly less aqueous humor cells and lower vitreous opacity scores (p < 0.05).
A sustained release of the drug from the NPs is important as a continuous exposure of the tumor cells to anticancer drugs of a relatively lower but safer concentration that gives little chance for the tumor blood vessels to grow, resulting in much better efficacy and fewer side effects than intermittent chemotherapy.
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As expected, AX-DOX minduces induce much better antitumor efficacy than free DOX at the same dosage, which is consistent with the in vitro CCK-8 assay findings.
Narrow-wavelength lamps generated much better clinical efficacy than broad-wavelength lamps.
Concerning the measure of the apoptotic fraction, no important differences were noted between SQ-gem/isoCA-4 NAs and the other treatments too, whereas these multidrug SQ-gem/isoCA-4 nanoassemblies displayed much better anticancer efficacy in vivo.
In vivo antitumor activity of the DOX/FA-PEG-P HB-HO) NPs showeDOX/FA-PEG-P HB-HOerapeutic efficacy in inhibiting tumor growth, anDOX/FA-PEG-P HB-HOumor volume was 178.91 ± 17.43 mm, significantly smaller than normal saline control group (542.58 ± 45.19 mm) which shows that these NPs are effective in selective DOX/FA-PEG-P HB-HONPsr drug to the folate receptor-overexpreshowedancer cells.
But it would be a fairly modest amount, says Perkins: "Most [investigators] are not willing to stockpile this material in any serious quantity without much better data about its efficacy in animals".
[ 46, 52] Hence, it is the current belief of many clinical trial neuro-oncologists that PFS is a much better indicator of treatment efficacy than the response rate.
Modulation of the patient's immune system combined with anti-tumor treatments offers the prospect of tailoring treatments much more precisely and better efficacy for patients with advanced lung cancer.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com