Sentence examples for mt track from inspiring English sources

The Kif18A tail contains a second MT-binding domain that diffuses along the MT lattice, suggesting that it tethers the motor to the MT track.

The pitch of dynein-driven rotation is much shorter than the supertwist of the GMP-CPP MTs (∼6400 nm), suggesting that helical motility of dynein is independent from the helicity of the MT track.

In cells, the same MT track is used for both plus- and minus-end-directed transport.

(C ) When multiple dimers carry a cargo bead, helical directionality may be affected by the number and orientation of the motors associated with an MT track.

Instead, we propose that the helical pattern of bead movement may be determined by the conformations of dynein motors associated with the MT track.

The two motor domains of the dimer can bind to the same MT track, most likely in a compact, side-by-side configuration of the two AAA ring domains (Cho and Vale, 2012), and exhibit persistent unidirectional motion.

In turn, MT organization determines axonal transport progression: cargoes pause at polymer termini, suggesting that switching MT tracks is rate limiting for efficient transport.

While MT tracks form essential intracellular highways for the transport of cellular material, they are not static structures.

Therefore, it is very likely that all exocytotic carriers, including caveolae, utilize MT tracks for long-range transport when MTs are present in cells, and MT-based transport is required to ensure the fidelity of polarized transport.

Since caveolae recycle along MT tracks between the plasma membrane and endosomal compartments (Mundy et al., 2002; Tagawa et al., 2005), we imaged MT-based motility of caveolae by transfecting keratinocytes with EGFP-caveolin-1 and Cherry-tubulin.

As such, a reduction in the standard deviation of this Gaussian curve represents a direct measure of an increase in the amount of MT clustering as measured by overlapping MT tracks.