Sentence examples for mt towards from inspiring English sources

Klp2p, a member of the minus end-directed kinesin 14 protein family [24] then slides the "daughter" MT towards the minus end of the pre-existing one [23] in this way confining the overlap regions to the minus-ends of the MTs.

The KT initially interacts with the MT lateral surface (lateral attachment) and slides along the MT towards a spindle pole.

ATP binding draws loop11 and loop9 closer together; causing (1) tilting of most of the motor domain not contacting the MT towards the nucleotide-binding site, (2) rotation, translation, and extension of helix-α6 which we propose contributes to force generation, and (3) allows neck linker docking and biases movement of the 2nd head towards the MT plus end.

After this initial period, receptors reach a second phase in which they are transported by MTs towards the gradient source.

In brief, activation of the receptors induces remodeling of the cytoskeleton with preferential growth of the MTs towards the GC leading edge.

Secretory vesicles are transported from the Golgi apparatus to the plasma membrane by motor proteins which move along microtubules (MTs) towards the cell surface where they dock to the cell membrane, fuse and release their contents to the cell surface or to the matrix [12], [68], [69].

However, Oa1-deficient melanosomes are able to efficiently move on MTs towards the nucleus upon AF removal and show a similar capacity of recruiting the myosin Va tail domain compared with organelles in wild-type cells.

Consistent with a progressive depletion of MTs towards the cell periphery, organelle tracking outside the perinuclear area (Fig.  8A, NT out) resulted in a reduction of melanosome motility, which was further decreased upon nocodazole treatment (Fig.  8A, Nocodazole).

This would certainly impede tubulin diffusion towards MT ends and thus MT growth.

A typical IMA possesses a relatively stable, centrally located medial region, with anti-parallel MTs overlapping at their minus ends [9] with the distal plus ends undergoing repeated cycles of MT growth towards and shrinkage away from the cell poles [10], [11], [14].

MT: Contributed towards the conception and design of this study, reviewed the article for important intellectual content, and approval of the version to be published.