All samples were demagnetized stepwise: alternating field demagnetization (AFD) was performed to a maximum field of 80 mT using an in-line AFD system of the pass-through SRM and thermal demagnetization (ThD) was performed in air to a maximum temperature of 600 °C using a Natsuhara TDS-1 thermal demagnetizer.
I demagnetized at 2, 5 or 10 mT intervals up to a peak field of 150 mT (for samples demagnetized with DEM-95) or 100 mT (for samples demagnetized with the in-line demagnetizer).
Moreover, evidences of the involvement of ERK1/2 in regulation of PLIN2 expression and the growth of LDs [ 41] give support to our findings of increased protein expression of PLIN2 seen under MT-II stimulus, and is in line with the involvement of ERK1/2 in biogenesis of LDs induced by this PLA2 homologue.
5-FU induced a rise in p53 mRNA expression in mt p53 cell lines and in human papilloma virus positive wt p53 cell line, whereas significant decrease in p53 mRNA expression was found in wt p53 cell line.
To identify those regions with statistically significant changes of histone acetylation that parallel our gene expression analysis, we partitioned the ChIP-Seq peak datasets into WT, FDCP and MT-I on the one hand and ME-I, ME-L and MT-L on the other hand, in line with the major partition identified by clustering analysis of gene expression profiles.
Some samples were demagnetized using both the in-line demagnetizer and DEM-95; first they were demagnetized up to 100 mT using the in-line demagnetizer, and then further demagnetized from 110 to 150 mT using DEM-95.
In line with this, 1-MT treatment prevented both serotonin depletion and behavioral alterations.
Apart from the significant differences between groups, results showed that the condition in which the task was performed affected MT. In line with the hypothesis, the MT appeared to deteriorate in lying and provoking condition compared to sitting condition.
This subarea presumably represents MT. The location of subregions MT and MST from our group level data are in line with previous single subject data [16], [17], [37].
Trajectories of MTs (green line) in K-fibers were defined and normalized via Euler's rotation (see 'Materials and methods') such that the overall trajectory of all fibers pointed to the zenith.
These observations are in line with and extend the current understanding of the mechanisms behind MT in AU.
