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Paired-pulse facilitation in R552H heterozygotes was significantly (p < 0.01) enhanced at short interstimulus intervals (10 75 msec) as compared to that in wild-type littermates, with no detectable differences between genotypes at longer intervals.
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As compared to the prior Convention Season.
as compared with control fish.
pyramidale as compared to the str.
Despite the use of QT-prolonging antiemetics, the QTc interval following 4-h 14 mg/m romidepsin IV dosing was only moderately increased (maximum mean increase of 10.1 msec; upper bound of the 90% CI, 14.5 msec) compared with the preantiemetic baseline, and below the 20-msec threshold.
Significant impairments were observed in PPF at 20-, 160-, and 320-msec intervals in APP/CCL2 and at 20 msec in APP compared to WT mice (Fig. 2B).
The Wilcoxon matched pairs test revealed shorter response times for the continuous performance task (386 ± 85 msec) compared to the go/no-go task (418 ± 21 msec) and cued target detection task (473 ± 49 msec).
Fasted rats of 6 months of age presented a 26% increase in T1obs (364.2 vs 290.0 msec) and 55% increase in T2obs values (88.5 vs 57.1 msec) compared with their values in normally fed rats (Table 1).
Sprague Dawley (SD) rats are more sensitive to PPI-disruptive effects of apomorphine (APO) at long interstimulus intervals (ISIs) (60 120 msec) and less sensitive to PPI-enhancing effects of APO at short ISIs (10 30 msec) compared with Long Evans (LE) rats.
If the average delay in active scanning is 750 msec as in [4] and 1200 msec in passive scanning, the total portion of the scanning delay is 12.5% and 20%, respectively.
It increased significantly to 3.6 ± 0.3 msec, 4.6 ± 0.2 msec, and 3.8 ± 0.2 msec in 1 (p < 0.0 compared with control; n = 8), 10 (p < 0.05 compared with control; n = 8), and 20 nM (p < 0.05 compared with control; n = 8) QDs, respectively.
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