Exact(5)
Animals were killed by an overdose of pentobarbital immediately after the MRS examination.
Informed parental consent was obtained prior to the P MRS examination which was conducted after essential clinical imaging.
The patient group received the second MRS examination about 12 weeks after applying SSRIs treatment (Paroxetine, 20 mg/d).
A dedicated MRS examination optimizing the homogeneity of the temporal lobe is necessary to clarify the impact of lead exposure within the temporal lobe.
The ratio of (choline + creatine)/citrate from MRS examination was also found to correlate with the Gleason grade from biopsy, which in most cases correlates to the aggressiveness of prostate cancer [ 7].
Similar(55)
Performing repeated in vivo H MRS examinations, we recently observed increases in ML/Cho ratios in neuroblastoma xenografts during chemotherapy (Lindskog et al, unpublished observation).
A subset of two patients from a larger treatment and follow-up study underwent serial quantitative single-voxel MRS examinations of five anatomical sites.
MRS examinations, similar to conventional MRI scans, are associated with intense scanner noise caused by rapidly switching the gradient coils on and off.
A total of 33 spectra with short and 18 spectra with long TE were obtained from brain metastases during the MRS examinations.
Follow-up MRS examinations where completed only for four of the included patients, since some got a complete surgical resection of the metastasis, a few refused further examinations and some died shortly after the first or second examination (Table 1).
F = female, M = male, mets = metastases, a: three MRS follow-up examinations, b: two follow-up MRS examinations, *: brain metastases detected before primary cancer, KPS = Karnofsky Performance Score, RPA = Recursive Partitioning Analysis classification, TE = echo time, VOI1,2 = volume of interest, : voxel size: 15 × 15 × 15 mm, : 10 × 10 × 10 mm.
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