Developing novel and effective solutions to problems in engineering and in general involves moving through phases of synthesis and analysis, each of which has a unique set of requirements with regard to psychological processes, personal qualities, and environmental characteristics.
The products hadn't moved through phase I safety studies, and the outbreaks were much smaller and always ended within a few months.
We have seen how saddles and attractors can be created and annihilated by bifurcations, and how they can move through phase space in such systems.
This four-phase procedural model, considered a generalization of scientific method, begins with a triggering event, and subsequently moves through phases of exploration, integration, and resolution (Garrison, 2016).
According to the Kuznets theory of economic development and energy consumption, as countries grow richer they move through phases of primarily agriculture and resource dependent growth, into a process of industrialization and the installation of modern infrastructure; and finally into a phase of consumer driven growth relatively geared toward services and higher value manufacturing activities.
They found that provider actions, maternal characteristics, and past experiences influenced the speed with which mothers moved through phases in order to develop a connected relationship [ 11, 21].
However, with pharmaceutical companies moving through a phase of diminished returns and alternative hit identification strategies proving successful, it is more important than ever to understand how this approach can be used more effectively to increase the delivery of next generation therapeutics from high throughput screening libraries.
We are tuned in instead to our growing to-do lists and instead of moving through each phase, we stay committed to the go-go-go.
Whether CICs undergo similar cell cycle changes in vivo upon radiation and whether cycling CICs become susceptible to drugs targeting cells moving through G2 phase remain to be determined.
