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The differences between the cortical network in our vs. Gazzola et al's study (e.g. the involvement of posterior parietal areas in the latter) might in part be due to different responses to simple everyday action sounds, such as ripping a sheet of paper, than to sounds associated with finger movement sequences such as those required for playing the piano melodies in our study.
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This suggests that even a small amount of sensory experience with a movement sequence, such as watching it while listening to its accompanying soundtrack, shapes perception in that these movements were liked more and performed better.
Here we review recent behavioural and neurophysiological studies on manual actions that require to consider more than a single spatial location in the planning of the response, such as movement sequences, grasping, and movements around obstacles.
Therefore, we cannot exclude the possibility that patients with marked impairments of movement sequencing abnormalities had such marked impairment present from the beginning of the illness.
Eye-tracking is commonly used to examine observers' gaze behaviour during such medical image interpretation tasks, but analysis of eye movement sequences is limited.
A parallel training and supervision by a physiotherapist likely help the patient to avoid such wrong movement strategies and to relearn to make complex movement sequences, even if they seem risky in the beginning.
The putamen is interconnected with so many other structures, it works in conjunction with them to control many types of motor skills such as motor learning, performance [ 54], preparation [ 55] and movement sequences [ 56].
In creating movement sequences, Mr. Jones uses mathematical concepts.
All these movement sequences are reordered to form a new whole.
Finally, multiple spatial representations may reflect different spatial sequence reference frames such as movement sequences in extrinsic spatial coordinates in the rostral PMd and the posterior parietal cortex (Brown et al., 2013; Wiestler et al., 2014) and in intrinsic spatial coordinates in the caudal PMd (Wiestler et al., 2014).
Overall, the independent encoding of the spatial and temporal features of movement sequences in premotor areas endows the nervous system with the ability for adjustments of individual movement parameters which would not be possible with a fixed integrated representation such as in M1 alone.
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