Your English writing platform
Discover LudwigSuggestions(5)
Exact(17)
More than 10 ABC-type transporters are now known to facilitate the movement of cholesterol and other lipids across membrane bilayers.
The gene is involved in facilitating the movement of cholesterol in and out of cells and is thought to play a role in the development of heart disease, too.
Although many flux studies have been conducted in the past, the recent discoveries of the scavenger receptor B1 (SR-B1) and ATP binding cassette 1 (ABCA1), which mediate the movement of cholesterol between cells and extracellular acceptors, has led to increased interest in studies of cellular cholesterol flux.
Pectin, β-glucans, fructans, and gums have been identified as agents that can work through the production of a viscous matrix that hinders movement of cholesterol and bile acids into micelles as well as the subsequent uptake of micelles into the enterocyte.
The toxins do so, the team suggests, by interfering with the movement of cholesterol within cells.
This solubilization facilitates the movement of cholesterol from the bulk phase of the lumen to the surface of the enterocyte.
Similar(43)
This idea implies that after crossing the BBB, HCD is endocytosed by neurons, complexes with cholesterol in LEs/LYs and together with the NPC2 protein facilitates movement of stored cholesterol.
In healthy individuals, these proteins cooperate to aid the movement of unesterified cholesterol through the lysosome, to the cytosolic compartment of cells through the body [49].
Cholesteryl ester transfer protein (CETP) promotes the movement of esterified cholesterol from HDL to VLDL and LDL particles, in exchange for triglyceride.
The rate-limiting step for steroidogenesis is the movement of unesterified cholesterol into mitochondria where it can then be metabolized by CYP11A1 and other enzymes in the steroidogenic pathway (for review see ref. [ 45]).
However, the specific events that characterize the intracellular movement and distribution of cholesterol and other lipids are only poorly understood.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com