Sentence examples for movement defect in from inspiring English sources

To quantify the movement defect in morphants, we measured spontaneous coiling.

The highly specific and clinically active MEK inhibitor, CI-1040 was able to suppress the cell movement defect in early embryogenesis caused by CFC kinase mutations.

Third, we tested whether low-level galactose exposure in development, and the elevated gal-1P values that result, would impact the severity of the movement defect in GALT-null adult flies.

To investigate the cellular mechanisms that underlie the cell movement defects in zdia2 morphants, we used time-lapse CCD camera recording to observe cell behavior and protrusive activities in both stdMO and zdia2 morphants.

In vivo, FGFR and MEK inhibitors can prevent cell movement defects in BRAF CFC- and MEK CFC-expressing zebrafish embryos (Anastasaki et al., 2009).

We show that the expression of both BRAF and MEK kinase-activating and kinase-impaired CFC and melanoma alleles cause similar phenotypes with significant cell movement defects in early embryogenesis.

Whether the sluggish movement defect seen in adult apl-1 knock-down worms is due to the molting defect, starvation or a neurotransmission defect remains to be seen.

Additionally, because Smed-tph is required for serotonin biosynthesis [ 61– 63], the Smed-tph RNAi movement defect is in line with previous observations that the coordinated wave-like motion of the ventral cilia of planarians is controlled by serotonin [ 9, 64].

Given the very high percentage of both integrin-adhesome and muscle attachment gene knockdowns that yielded defects in muscle, we performed RNAi against a set of 10 knockdowns previously shown to produce a movement defect but not a subcellular defect in muscle (subset of genes from ref. 18) and, as expected, failed to find defects in muscle despite finding impaired movement.

A null mutation in the fax-1 gene causes a distinctive movement defect.

The answer was positive in that about 2.5% of wild-type GALT activity was sufficient to rescue most of the movement defect.